Synthesis, characterization and safety evaluation of raw materials for cyclodextrin fullerene derivatives

To further improved the water solubility of fullerene, a new cyclodextrin and fullerene derivative was synthesized in this paper. NMR, elemental analysis, spectral tunnel scanning electron microscopy X powder diffraction were used to characterize material. Spectral analysis showed that assembly had wide acromion at 343nm large tail band absorption range 350-600nm, indicating presence C60. From STM images, it can be inferred weak interaction between cavity tail-to-tail form regular linear arrangement. X-ray shows there have many characteristic peak 11, such as 2 θ =11.52° (d=7.68Å), =14.62° (d=6.05Å), =25.5° (d=3.49 Å), =29.62° (d=3.01Å), =31.68° (d=2.82 which proved fullerenes formed supramolecular polymers Through chemical safety tests, results no risk substances, pollutants, prohibited substances restricted samples could affect cosmetics. Phototoxicity, eye irritation/corrosiveness, skin irritation cytotoxicity not detected by toxicological test. This study provides technical data support for use derivatives cosmetic raw materials.